Impact of Covid-19 on the inner GPS of the brain

Abstract

The brain performs all the navigation work in the hippocampus, the
region responsible for spatial orientation and memory formation
like an internal global positioning system (GPS). COVID-19 has
affected daily life in unprecedented ways decreasing hippocampal
activity. The viral entry can alter neurotransmitter systems causing
cognitive dysfunction such as learning and memory impairment.
However, the accompanying alteration of neurotransmitters like
dopamine (DA) and serotonin (5-HT) resulting neurocognitive
changes remain poorly understood.